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M94A0240.TXT
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1994-10-08
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Document 0240
DOCN M94A0240
TI [Studies on neurogenic bladder due to human T-lymphotropic virus type-I
associated myelopathy (HAM)]
DT 9412
AU Imamura A; Department of Urology, Faculty of Medicine, Kagoshima
University,; Japan.
SO Nippon Hinyokika Gakkai Zasshi. 1994 Jul;85(7):1106-15. Unique
Identifier : AIDSLINE MED/94359091
AB Fifty cases of untreated human T-cell lymphotropic virus type I (HTLV-I)
associated myelopathy (HAM) were evaluated by urodynamic studies to
clarify the nature of urinary disturbance and to find out suitable
urological treatment. Both irritative and obstructive symptoms coexisted
in the HAM patients. 38% of the patients experienced only urinary
symptoms throughout the affected period. A main cause of frequency was
detrusor hyperreflexia at filling phase, which was found in 58% of the
patients. However, decreased effective bladder capacity due to large
amount of residual urine was possibly an another cause of frequency.
Detrusor sphincter dyssynergia was the main cause of difficulty of
urination, but in some cases underactive detrusor at voiding phase was
also the cause of difficulty of urination. Hydronephrosis was observed
in only 5 kidneys, although as many as 30 out of 46 cases (65.2%) showed
bladder deformity. 17 cases (34%) had urinary tract infection at first
visit. As the activity of daily living was deteriorated, the mean volume
of residual urine, incidence of detrusor hyperreflexia and detrusor
sphincter dyssynergia were all increased. Medical treatment was
effective to relieve subjective symptoms, but urodynamic examination did
not necessarily review improvement. Intermittent catheterization was
needed and successful in 64% of all cases. Patients with HAM must be
carefully followed up by urologists.
DE Adult Aged Bladder/PHYSIOPATHOLOGY Bladder,
Neurogenic/*ETIOLOGY/PHYSIOPATHOLOGY English Abstract Female Human
Male Manometry Middle Age Paraparesis, Tropical
Spastic/*COMPLICATIONS Urodynamics JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).